TUBERCULOSIS PADA ANAK
DOI:
https://doi.org/10.59003/nhj.v5i7.1787Keywords:
Tuberculosis; Pediatric tuberculosis; Childhood TB; Diagnosis; Risk factors; BCG vaccination; Prevention; Clinical manifestationsAbstract
Tuberculosis (TB) in children remains a significant global health problem, particularly in countries with high transmission rates. Children are more susceptible to rapid progression into severe forms of TB, such as TB meningitis and miliary TB, due to their immature immune systems. Diagnosing TB in children is challenging because symptoms are often nonspecific and bacterial loads are low, leading to frequent negative bacteriological results. Common clinical manifestations include persistent cough, prolonged fever, weight loss, and failure to thrive. Major risk factors include close contact with adult TB cases, malnutrition, and immunocompromised conditions. Diagnostic approaches require a combination of clinical evaluation, radiological examination, and immunological tests such as the tuberculin skin test or IGRA. Treatment follows standard antituberculosis drug regimens according to national guidelines. Preventive measures, including BCG vaccination and routine screening of household contacts, play a crucial role in reducing the incidence and complications of TB in children. Overall, early detection and comprehensive management are essential to decrease morbidity and mortality associated with pediatric TB.
Downloads
References
Abdiana R, Fitria S. (2019). Penatalaksanaan Tuberkulosis pada Anak Usia 6 Thaun dengan Pendekatan Kedokteran Keluarga. Medula, 3. Fakultas Kedokteran Universitas Lampung.
PPTI. (2010). Buku Saku Perkumpulan Pemberantasan Tuberkulosis Indonesia (PPTI), The Indonesiaan Association Against Tuberculosis. 66, 9-10.
Yustikarini K, Magdalena S. (2015). Faktor Risko Sakit Tuberkulosis pada Anak yang Terinfeksi Mycobacterium Tuberculosis. Sari Pediatri, 17 (2): 136-140.
Handayani L. (2024). Studi Epidemiologi Tuberkulosis Paru (TB) di Indonesia: Temuan Survey Kesehatan Indonesia (SKI) 2023. J Kendari Kesehat Masy, 4 (1): 1-9.
Kemenkumham DP. (2023). Laporan Program Penanggulangan Tuberkulosis Tahun 2022. Kemenkes RI, 1-156.
Bussi C, Gutierrez MG. (2019). Mycobacterium tuberculosis infection of host cells in space and time. FEMS Microbiol Rev, 43 (4): 341-361.
Kementerian Kesehatan Republik Indonesia. (2017). Pedoman Nasional Pengendalian Tuberkulosis. Jakarta: Direktorat Jenderal Pengendalian Penyakit Dan Penyehatan Lingkungan, Kementerian Kesehatan Republik Indonesia.
Rahajoe NN, Supriyatno B, Setyanto DB. (2012). Buku Ajar Respirologi Anak. Edisi Pertama. Jakarta: Ikatan Dokter Anak Indonesia.
Kementerian Kesehatan Republik Indonesia. (2023). Petunjuk Teknis, TataksanaTuberkulosis Anak Dan Remaja Indonesia.
Khairunnisa SA, Puspitasari IM. (2023). Review : Efek Samping Obat Antituberkulosis Oral Lini Pertama Pada Anak. Farmaka, 21 (2): 197-205.
Marais BJ, Gie RP, Schaaf HS. (2004). The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era. Int J Tuberc Lung Dis, 8 (4): 392-402.
Cruz AT, Starke JR. (2014). Clinical manifestations of tuberculosis in children. Paediatr Respir Rev,15 (4): 453-461.
Detjen AK, DiNardo AR, Leyden J. (2015). Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis. Lancet Respir Med, 3 (6): 451-461.
Chiang SS, Swanson DS, Starke JR. (2015). Diagnosis of tuberculosis in children: past, present, and future. Pediatr Infect Dis J, 34 (9): 1014-1019.
Sia IG, Wieland ML.(2011). Current concepts in the management of tuberculosis. Mayo Clin Proc, 86 (4): 348-361.
Shingadia D, Novelli V. (2003). Diagnosis and treatment of tuberculosis in children. Lancet Infect Dis, 3 (10): 6240-632.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Irwandi

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
NHJ is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Articles in this journal are Open Access articles published under the Creative Commons CC BY-NC-SA License This license permits use, distribution and reproduction in any medium for non-commercial purposes only, provided the original work and source is properly cited.
Any derivative of the original must be distributed under the same license as the original.



















